Diagnosis of gastric cancer by measuring the urinary porphyrins after oral administration of 5-aminolevulinic acid (ALA).

Diagnosis of gastric cancer by measuring the urinary porphyrins after oral administration of 5-aminolevulinic acid (ALA). - Diagnosis of gastric cancer using urinary porphyrins.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000032048

Enrollment

Registered

2018-04-01

Start date

2015-09-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Measuring the urinary and serum levels of porphyrins after oral administration of 5-ALA (300mg) at the following points. 1. Gastric cancer patients 30 cases 1) before gastrectomy 2) after gastre

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) >=20 years old, <85 years old 2) Gastrectomy is scheduled for cSE gastric cancer. 3) patients who provide a written informed consent

Exclusion criteria

Exclusion criteria: 1) Patients with severe anamnesis (Malignant hypertension. With severe congestive heart failure. Severe liver failure. Myocardial infarction within 3 months. End-stage cirrhosis. Poorly controlled diabetes. Severe pulmonary fibrosis. Interstitial pneumonia activity) 2) Patients who are able to orally intake foods. 3) Patients with porphyria or hypersensitivity to porphyrins allergy 4) Cancer patients within 5 years after treatment.

Design outcomes

Primary

Measure	Time frame
The urinary and serum levels of porphyrins (5-ALA, uroporphyrin I and III, coproporphyrin I and III, protoporphyrin IX) after oral administration of 5-ALA in gastric cancer patients before and after gastrectomy and non-cancer patients.	—

Countries

Japan

Contacts

Public ContactKentaro Kishi

Osaka Police Hospital Department of gastrointestinal surgery

kishi-ke@oph.gr.jp06-6771-6051

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026