Relationship between temporal biomarker profiling after atrial fibrillation catheter ablation and the atrial fibrillation recurrence and thromboembolic event

Relationship between temporal biomarker profiling after atrial fibrillation catheter ablation and the atrial fibrillation recurrence and thromboembolic event - Temporal biomarker profiling after atrial fibrillation catheter ablation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000031954

Enrollment

200

Registered

2018-03-28

Start date

2018-03-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with a confirmed diagnosis of atiral fibrillation who are scheduled to undergo catheter ablation. Patients who have used edoxaban prior to enrollment in this study. Patients who are 20 or more than 20 years old. Patients who receive an explanation about this study and give written informed consent (sequential registration, in principle).

Exclusion criteria

Exclusion criteria: Patients scheduled to enroll in or participating in another clinical study. Patients in whom catheter ablation is contraindicated. Patients considered to be unsuitable for this study for other reasons.

Design outcomes

Primary

Measure	Time frame
Relationship between temporal changes of various biomarkers before and after catheter ablation of atrial fibrillation and recurrence of atrial fibrillation. Before catheter ablation, immediately after ablation, 1 day after ablation, at 1, 3, and 6 months after ablation, and at recurrence of atrial fibrillation cTnT, NT-proBNP, PT-INR, APT, D-dimer, SFMC, TAT, PT fragment F1+2, Fib, AT-III, t-PA, PAI-1, vWf, sTM	—

Measure

Time frame

Relationship between temporal changes of various biomarkers before and after catheter ablation of atrial fibrillation and recurrence of atrial fibrillation. Before catheter ablation, immediately after ablation, 1 day after ablation, at 1, 3, and 6 months after ablation, and at recurrence of atrial fibrillation cTnT, NT-proBNP, PT-INR, APT, D-dimer, SFMC, TAT, PT fragment F1+2, Fib, AT-III, t-PA, PAI-1, vWf, sTM

—

Countries

Japan

Contacts

Public ContactYuki Iwasaki

Nippon Medical School Hospital The department of cardiovascular medicine

iwasaki@nms.ac.jp03-3822-2131

Outcome results