Augmentation of positive valance system-focused cognitive behavior therapy by inaudible high-frequency sound therapy: A placebo-controlled randomized trial

Augmentation of positive valance system-focused cognitive behavior therapy by inaudible high-frequency sound therapy: A placebo-controlled randomized trial - Augmentation of positive valance system-focused cognitive behavior therapy by inaudible high-frequency sound therapy: A placebo-controlled randomized trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031948

Enrollment

Registered

2018-04-01

Start date

2018-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anhedonia

Interventions

Positive valence system-focused cognitive behavior therapy with inaudible high-frequency sounds Positive valence system-focused cognitive behavior therapy is a psychotherapy for anhedonia. The eigh

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (a) Anhedonic symptoms (Snaith-Hamilton Pleasure Scale score <=20) (b) Depressive symptoms are mild or severer (GRID Hamilton depression rating scale <=8) (c) Ages 18 years or older

Exclusion criteria

Exclusion criteria: (a) No current psychotic disorders at baseline assessed by the Mini-International Neuropsychiatric Interview (MINI) (b) No current manic episode at baseline assessed by MINI (c) No severe substance use disorders at baseline assessed by MINI (d) No serious suicidal ideation at baseline assessed by MINI (e) No severe or unstable physical disorders or major cognitive deficits at baseline (f) Other problems that can be seriously obstacle for conducting cognitive behavior therapy

Design outcomes

Primary

Measure	Time frame
Anhedonia symptoms assessed by the Snaith-Hamilton Pleasure Scale (SHAPS) from week 1 to 12	—

Secondary

Measure	Time frame
Anhedonia symptoms assessed by the Snaith-Hamilton Pleasure Scale-clinician administered (SHAPS-C) at week 12	—

Countries

Japan

Contacts

Public ContactMasaya Ito

National Center of Neurology and Psychiatry National Center for Cognitive-Behavior Therapy

masaya-ito@umin.ac.jp+81-42-341-2711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026