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Clinical Significance of Monitoring by Interferon-Gamma Releasing Assay (IGRA) in Patients with Non-Small Cell Lung Cancer receiving Checkpoint Inhibitor Treatment

Clinical Significance of Monitoring by Interferon-Gamma Releasing Assay (IGRA) in Patients with Non-Small Cell Lung Cancer receiving Checkpoint Inhibitor Treatment - Clinical Significance of Monitoring by Interferon-Gamma Releasing Assay (IGRA) in Checkpoint Inhibitor Treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000031881
Enrollment
30
Registered
2018-03-24
Start date
2018-07-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-Small Cell Lung Cancer

Interventions

None listed

Sponsors

Osaka Prefectural Hospital Organization Osaka Habikino Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Unresectable or progressive non-small cell lung Cancer patient treated with ICI alone regardless of the number of the previous regimens. 2.Twenty years old or older patient at registration. 3. Patients with performance status 0-2. 4. Patients with the measurable lesion. 5. Written Informed Consent from the patient

Exclusion criteria

Exclusion criteria: 1.Patient with an active heterochronous or synchronous overlap cancer (carcinoma-insitu or cured intramucosal canceris excluded from overlap cancer) 2 Patient with active liver disease (ex. HBV-DNA positive, autoimmune hepatitis, anliver cirrhosis). 3 Female patient with the possibility (intention) of the pregnancy. Patient whom the Doctor in charge judged to be inappropriate as an object of this study.

Design outcomes

Primary

MeasureTime frame
Association between IFN-gamm and efficacy, immune-related adverse events, or Hyper progressive Disease in Patients with Non-Small Cell Lung Cancer receiving ICI

Countries

Japan

Contacts

Public ContactHidekazu Suzuki

Osaka Habikino Medical Center Thoracic Oncology

suzukih@ra.opho.jp+81-72-957-2121

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026