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Reduction of wound swelling using herbal medicine, a combination of keishibukuryogan and jidabokuippo, in patients undergoing craniotomy: a randomized controlled trial

Reduction of wound swelling using herbal medicine, a combination of keishibukuryogan and jidabokuippo, in patients undergoing craniotomy: a randomized controlled trial - Reduction of wound swelling using herbal medicine in patients undergoing craniotomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000031827
Enrollment
60
Registered
2018-03-21
Start date
2018-03-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unruptured cerebral aneurysm

Interventions

Patients with herbal medicine 1. Receiving keishibukuryogan (7.5g per day) from 2 days prior surgery to the day before surgery. 2. After confirming that consciousness and swallowing on the 1st posto

Sponsors

Department of Neurosurgery, Iwate Medical University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Undergoing neck clipping through fronto-temporal craniotomy for unruptured cerebral aneurysm in our institute. 2)Age:74 or less and 20 or more. 3) Possible to administer jidabokuippo and keishibukuryogan. 4)Obtaining informed consent.

Exclusion criteria

Exclusion criteria: 1)Expecting deterioration of symptoms such as liver function and Gastrointestinal disorders by administration of herbal medicine. 2)Presence of dysphagia. 3)Determining as "unsuitable for inclusion into this study" by an investigator.

Design outcomes

Primary

MeasureTime frame
Differences of thickness of soft tissues on skull displayed on computed tomography performed before and after surgery (the 4th and 7th postoperative days)

Countries

Japan

Contacts

Public ContactTakahiro Koji

Iwate Medical University School of Medicine Neurosurgery

thkoji@iwate-med.ac.jp81-19-651-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026