Gastric cancer
Conditions
Interventions
Study arm: Extensive peritoneal lavage. The peritoneal cavity will be washed with 10 liters of normal saline (1 liter each cycle for 10 cycles).
Control arm: Standard treatment. The peritoneal cavity
Sponsors
National University Hospital, Singapore
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients who have T3 (subserosal) or T4 (serosal) disease based on CT scan and intra-operative inspection with any N staging and M0 gastric cancer. 2.Patients planned for open or laparoscopic gastrectomy. 3.Patients undergoing gastrectomy with curative intent. 4.Lower age limit of research subjects 21 years old and upper age limit of 80 years old. 5.Ability to provide informed consent 6.Ability to come back for study visits throughout the 3 years duration after surgery 7.Patients are local residents
Exclusion criteria
Exclusion criteria: 1.Patients who undergo a palliative gastrectomy. 2.Patients who undergo a gastrectomy as emergency. 3.Vulnerable persons under age of 21. 4.Patients receiving neoadjuvant therapy. 5.Patients presented with life-threatening bleeding from tumour 6.ASA score of 4 & 5 7.Patients with another primary cancer within last 5 years 8.Patients with gross peritoneal and liver metastasis at surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease free survival Peritoneal recurrence rate | — |
Countries
Japan,Asia(except Japan)
Contacts
Public ContactProf. Jimmy So
National University Hospital, Singapore Department of Surgery
Outcome results
None listed