Effect of guava and vitamin C supplementation on experimental gingivitis. A randomized clinical trial

Effect of guava and vitamin C supplementation on experimental gingivitis. A randomized clinical trial - Guava and vitamin C suplementation on experimental gingivitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031772

Enrollment

Registered

2018-03-17

Start date

2017-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-smoker healthy young population

Interventions

Guava fruit including skin and flesh, 200 gr/day for 28 days Synthetic Vitamin C, 200 mg/day for 28 days Water, packed in cup of 250 ml/day, for 28 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy adult, non-smokers, no probing pocket depth more than 4 mm at any site and bleeding on probing less than 10%.

Exclusion criteria

Exclusion criteria: (1) having systemic diseases, (2) being pregnant or giving breastfeeding, (3) having physical or mental handicaps that may interfere with an adequate oral hygiene, (4) having a history of drug abuse, (5) using nonsteroidal or steroidal anti-inflammatory drugs, analgesic or antibiotics within 6 weeks before the study, (7) having untreated carious lesions, crowns or orthodontic appliances in the lower jaw.

Design outcomes

Primary

Measure	Time frame
Gingival inflammation during exprimental gingivitis	—

Secondary

Measure	Time frame
Plaque accumulation during experimental gingivitis	—

Countries

Asia(except Japan)

Contacts

Public ContactProf Dr Ubele van der Velden

Academisch Centrum Tandheelkunde Amsterdam Department of Periodontology

u.vd.velden@acta.nl+31205980380

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026