Study of body fluid management in patients after cardiac surgery by preoperative administration of tolvaptan

Study of body fluid management in patients after cardiac surgery by preoperative administration of tolvaptan - Study of body fluid management by preoperative administration of tolvaptan

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031762

Enrollment

Registered

2018-04-01

Start date

2018-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac disease

Interventions

administration of tolvaptan

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Person undergoing cardiac surgery 2.Those who have consent

Exclusion criteria

Exclusion criteria: 1.Allergy of this drug 2.serious liver/renal dysfunction 3.Dialysis patients 4.Emergency surgery case 5.Those who have made a request for refusal in participating in this research 6.Others who judged that the research director is inappropriate as the research subject

Design outcomes

Primary

Measure	Time frame
The number of days until the peoperative body weight plus minus 1kg	—

Secondary

Measure	Time frame
AVP, renin, aldosterone, BUN, Cre, eGFR, Na, K, Alb, osmotic pressure postoperative weight / urine volume, number of hospital days, time to withdrawal of the ventilator, number of thoracic punctures, postoperative atrial fibrillation, infection, death	—

Countries

Japan

Contacts

Public Contactkeito Suzuki

Nihon University School of Medicine Cardiovascular Surgery

suzuki.keito@nihon-u.ac.jp81-3-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026