Periodontitis
Conditions
Interventions
Following SRP, Er:YAG laser irradiation is performed with water spray at 30 Hz and 50-80 mJ at panel setting.
SRP
Sponsors
Tokyo Medical and Dental School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patient who is receiving periodontal therapy in Dental Hospital of Tokyo Medical and Dental University 2. Single rooted tooth with attachment loss, pocket depth of 5 mm or more, BOP (+), tooth mobility class I or less and bone defect depth of 3 mm or more 3. Based on the split mouth design, there are 1 or more teeth that meet the above conditions in 2 quadrants of the mouth.
Exclusion criteria
Exclusion criteria: 1. Having systemic disease that can affect periodontal condition, such as diabetes 2. Smokers 3. In case of pregnancy or lactation 4. The history of anesthesia allergy 5. Receiving antimicrobial agent in the last 3 months 6. Having an infectious disease, such as hepatitis or HIV
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Attachment Level (CAL) at 1 and 2 weeks and 1, 3 , 6 and 12 months after treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Proving pocket depth (PPD), Gingival recession, tooth mobility, Bleeding on Probing (BOP), Plaque Index(PI), Gingival Index (GI), total number of periodontal bacteria (P.gingivalis, T. forsythia, T. denticola) and IL-1b level in gingival crevicular fluid at 1 and 2 weeks and 1, 3, 6 and 12 months after treatment. Evaluation of discomfort and pain by Visual Analog Scale (VAS) method up to 4 weeks after treatment. Evaluation of X-ray after 6 and 12 months after treatment. | — |
Countries
Japan
Contacts
Public ContactAkira Aoki
Tokyo Medical and Dental University Department of Periodontology, Graduate School of Medical and Dental Sciences
Outcome results
None listed