Study on the association of reflux esophagitis and oral microbiota.

Study on the association of reflux esophagitis and oral microbiota. - Influence of oral microbiota for reflux esophagitis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000031574

Enrollment

Registered

2018-03-05

Start date

2016-05-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reflux esophagitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) over 20 year old 2) Informed consent about this research has been obtained with participants in writing form.

Exclusion criteria

Exclusion criteria: 1) daily usage of steroids, immunosuppresive and anticancer drugs 2) 20 or fewer teeth 3) using antibiotics during use or within 1 month 4) During pregnancy, lactating, a woman who may be pregnant 5) history of allergy to proton pump inhibitor 6) A case of a history of resection of the gastrointestinal tract except for appendectomy 7) the research director judged inappropriate as the subject of this resea

Design outcomes

Primary

Measure	Time frame
Healthy volunteers, patients with reflux esophagitis or eosinophilic esophagitis donated the fecal, saliva, periodontal pocket fluid and scraching samples of esophagus mucous. We then investigate the bacterial communities using 16S rRNA gene sequencing method.	—

Countries

Japan

Contacts

Public ContactTsuyoshi Mishiro

Shimane university school of medicine Division of gastroenterology

tmishiro@med.shimane-u.ac.jp0853-20-2190

Outcome results