1 Localized prostate cancer 2 Local recurrent prostate cancer after definitive radiotherapy
Conditions
Interventions
Cryosurgery
Sponsors
Jikei University School of Medicine
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Localized prostate cancer 1)Gleason score, under7 2) PSA <20ng/ml 3) Clinically significant cancer proven by MRI/US fusion biopsy and mltiparametric MRI imaging. 4) Except for targeted lesion, no MRI findings and Biopsy gleason score by transperineal saturation biopsy is under 6 5) Clinical T stage <T3a 2. Radiorecurence prostate cancer 1) Local recurrence prostate cancer after definitive radiotherapy 2) No distant metastasis 3) The serum PSA level is less than 20 ng/ml before salvage Tx 4) PS 0-1 5) No hormone therapy before recurrence.
Exclusion criteria
Exclusion criteria: 1) Active cancer in other organ 2) Uncontrol HT, DM and ischmic heart disease 3) Severe brain disease 4) Collagen disease 5) uncontroled DM 6) uncontroled heart disease 7) The prostatectomy was performed before 6) Using steroid drug, excluding ointment 8) Attnding physician determines that the ineligible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biochemical recurrence free survival | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Overall survival (2) Clinical progression free survival (3) Prostate cancer specific survival (4) Salvage treatment free survival (5) biopsy results (6) Adverse events (7) QOL analysis | — |
Countries
Japan
Contacts
Public ContactHiroshi Sasaki
Jikei University School of Medicine Urology
Outcome results
None listed