Gastrointestinal surgery
Conditions
Interventions
use of Olanexidine gluconate for surgical site before surgery
use of Povidone iodine for surgical site before surgery
Sponsors
Keio University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients that satisfy all of the below requirements. 1) Surgery for gastrointestinal, such as gastrectomy, esophagectomy, hepatectomy and pancreaticoduodenectomy with wound classification classII 2)The age is older than 20 years of age. 3) Having provided voluntary written consent for participation in this study.
Exclusion criteria
Exclusion criteria: 1)Patients contraindicated for Olanexidine gluconate or Povidone iodine 2) Follow-up failure due to pass-away or other reasons. 3) Patients who have active infectious disease. 4)Patients who were prescribed antibiotics day before surgery. 5)Urgent surgery or surgery with sterilization to the mucosal surface or wound. 6)Patients judged by investigators ineligible due to seriousness of patients condition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative 30-day surgical site infection (SSI) rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative 30-day superficial incisional SSI rate, deep incisional SSI rate, organ/space SSI rate, rate of positive bacterial wound culture, and their strains, and toxicity and allergies events (erythema, symptoms of allergy) rate. | — |
Countries
Japan
Contacts
Public ContactMasashi Takeuchi
Keio University, School of Medicine Department of Surgery
Outcome results
None listed