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Assessment of brain mechanisms underlying effect of a ketogenic meal on cognitive function

Assessment of brain mechanisms underlying effect of a ketogenic meal on cognitive function - Assessment of brain mechanisms underlying effect of a ketogenic meal on cognitive function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000031539
Enrollment
20
Registered
2018-03-01
Start date
2018-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

A single serving of the ketogenic meal consisted of 50 g of Meiji817-B (Meiji Co., Ltd., Tokyo, Japan), which contains 20 g of medium chain triglycerides. A single serving of the 50 g placebo meal co

Sponsors

National Center of Neurology and Psychiatry
Lead Sponsor
Meiji Holdings Co., Ltd.
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Elderly people who is between 60 and 75 years old

Exclusion criteria

Exclusion criteria: 1. Left-handedness 2. History of psychiatric illnesses 3. History of significant head trauma or neurological disorders 4. Any medical condition that could affect brain function/morphology 5. Pregnancy 6. Any contraindication to MRI scanning (e.g. metal implants, cardiac pace-maker) 7. People who don't want to be informed of incidental findings 8. Allergies to milk, soybean, or pork 9. Lactose intolerance 10. Any other person whom the principal investigator has determined to be unsuitable as a participant of the study.

Design outcomes

Primary

MeasureTime frame
1. Changes in brain activation related to cognitive enhancement by a ketogenic meal 2. Brain morphology related to individual difference in sensitivity to cognitive enhancement effect by a ketogenic meal

Countries

Japan

Contacts

Public ContactYukihito Yomogida

National Center of Neurology and Psychiatry Department of Mental Disorder Research, National Institute of Neuroscience

yomogida@ncnp.go.jp042-341-2711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026