Breast cancer
Conditions
Interventions
This study uses scalp cooling device (Paxman cooler, U.K.) for about 180 minutes during receiving chemotherapy.(30 minutes before and 90 minutes after chemotherapy)
Sponsors
National Hospital Organization Kyushu Cancer Center
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1)Histologically confirme breast cancer 2)Stage I, II or III 3)Female aged 20 to 75 years old. 4)The case for that is planned anthracycline, taxane-based chemotherapy and in that hair loss is expected. 5)No history of the chemotherapy for the malignant tumor 6)Signed informed consent of the patient for registration.
Exclusion criteria
Exclusion criteria: 1)Chilly allergy 2)Cold agglutinin disease 3)Any scalp skin tumor 4)History of radiation for head 5)Temporomandibular disorder or disease to a chin 6)Any other cases who are regarded as inadequate for study enrollment by the attending doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of grade 0 or 1 of hair loss, according to CTCAE ver4.0 classification | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of hair loss restraint in each evaluation timing Hair loss accompanying symptom Hair loss period Safety Adverse events Influence of the hair loss after the chemotherapy | — |
Countries
Japan
Contacts
Public ContactChinami Koga
National Hospital Organization Kyushu Cancer Center Breast Oncology
Outcome results
None listed