A pilot study of endoscopic hand-suturing for mucosal defects after colorectal endoscopic submucosal dissection

A pilot study of endoscopic hand-suturing for mucosal defects after colorectal endoscopic submucosal dissection - NCCH-1717

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031512

Enrollment

Registered

2018-04-01

Start date

2018-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal neoplasms

Interventions

endoscopic hand-suturing (EHS) for mucosal defects immediately after colorectal endoscopic submucosal dissection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) colorectal adenoma or adenocarcinoma 2-5cm in size scheduled for ESD 2) age20 years old or more 3) PS 0-1 4) obtained written informed consent

Exclusion criteria

Exclusion criteria: 1) high risk of post-ESD bleeding a) Plt less than 50000/mm3 or PT-INR 2 or more b) Liver chirrosis Child Pugh score B-C c) chronic kidney disease needed hemodyalysis 2) unable to discontinue antithrombotic drug according to Japanese guidelines 3) prior abdominal or pelvic surgery 4) prior radiotherapy for abdomen or pelvis 5) thought ineligible by attending endoscopist 4)

Design outcomes

Primary

Measure	Time frame
successful closure rate	—

Secondary

Measure	Time frame
1. Sustained closure rate post 3-4 days after ESD (only rectum and sigmoid colon) 2. Post-ESD bleeding rate 3. Perforation rate 4. other complication rate 5. procedure time for closure	—

Countries

Japan

Contacts

Public ContactSeiichiro Abe

National Cancer Center Hospital Endoscopy Division

seabe@ncc.go.jp03-3542-2511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026