Study of the effect of topical trehalose on postoperative clinical course after trabeculectomy

Study of the effect of topical trehalose on postoperative clinical course after trabeculectomy - Effect of topical trehalose on the filtering bleb after trabeculectomy

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031482

Enrollment

Registered

2018-02-26

Start date

2019-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

instillation of 5% trehalose 4times a day for one month after surgery in addition to the other regular postoperative medications instillation of sterile saline 4times a day for one month after surge

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: trabeculectomy naive eye

Exclusion criteria

Exclusion criteria: eyes which were previously treated by trabeculectomy fellow eye of the participant

Design outcomes

Primary

Measure	Time frame
postoperative volume of the filtering bleb for 6 months after surgery	—

Secondary

Measure	Time frame
level of intraocular pressure control for 6 months after surgery	—

Countries

Japan

Contacts

Public ContactMitsuru Nakazawa

Hirosaki University Graduate School of Medicine Department of Ophthalmology

mitsuru@hirosaki-u.ac.jp0172-39-5094

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026