Low back pain
Conditions
Interventions
Duloxetine (40 mg) will be orally administered 2h before surgery, then postoperative pain will be assessed.
Diazepam (4 mg) will be orally administered 2h before surgery as active placebo group.
Sponsors
Fukushima Medical University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients scheduled to undergo posterior lumbar interbody fusion will be enrolled in this study. The study population included patients aged 20-80 years who are American Society of Anesthesiologists physical status I-II and who agreed to participate in this clinical trial.
Exclusion criteria
Exclusion criteria: 1) Patients who can not use duloxetine 2) Patients who need antipsychotics or antidepressants and who are schizophrenia, bipolar disease, or depression within a year before registration of this study. 3) Patients who needs opioids 4) Patinets who can not agree the protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain using visual analogue scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Consumption of postoperative analgesics | — |
Countries
Japan
Contacts
Public ContactHideaki Obata
Fukushima Medical University Hospital Center for Pain Management
Outcome results
None listed