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Preliminary study, by chewing gum, to evaluate the changes on saliva component, oral hygiene and masticatory function.

Preliminary study, by chewing gum, to evaluate the changes on saliva component, oral hygiene and masticatory function. - Evaluation of the saliva metabolomics, and the changes in oral hygiene and masticatory function.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000031392
Enrollment
30
Registered
2018-02-20
Start date
2017-11-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Saliva are collected four weeks before chewing tasteless and odorless gum [about 10 minutes, 7 times per day], just before, one day after, and four weeks after, and carried out metabolome analysis. I

Sponsors

Taiyo school of dental hygiene
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 17 students (20-21 years old), who got their consent, in Taiyo school of dental hygiene were chosen as volunteers. Through public offering by posting, we reminded them that participate in research is voluntary and is not mandatory. They receive informed consent for research, and participate in this research with agreement.

Exclusion criteria

Exclusion criteria: The following persons are excluded from subjects: Persons who have some medical history in mind and body, who have with gingivitis and periodontitis, who need basic periodontal therapy, teeth requiring treatment, those having a tooth under treatment, those taking ordinary medicines, daily life Those that frequently chew gum.

Design outcomes

Primary

MeasureTime frame
Saliva metabolome analysis after one-day and four-weeks chewing gum of tasteless and odorless (7 times / day, 10 minutes / time).

Secondary

MeasureTime frame
Evaluation of oral condition (salivary secretion rate, salivary cariogenic bacterial level, plaque formation, gingivitis, etc.), mental health, and masticatory abilities.

Countries

Japan

Contacts

Public ContactAkane Takenouchi

Taiyo school of dental hygiene Daytime class

kyoumu@taiyodhs.ac.jp03-5810-8020

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026