pathology research of secondary osteoporosis in adult patients with type 2 diabetes mellitus: bone microarchitecture assessed by HR-pQCT

pathology research of secondary osteoporosis in adult patients with type 2 diabetes mellitus: bone microarchitecture assessed by HR-pQCT - T2DM HR-pQCT study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000031382

Enrollment

240

Registered

2018-04-01

Start date

2018-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabete mellitus

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.adult patients of 20 years and over with type 2 diabetes mellitus 2.healthy control each 120 cases

Exclusion criteria

Exclusion criteria: 1.a patient with type 1 diabetes mellitus 2.a patinet with thyroid disease, parathyroid disease, celiac or inflammatory bowel disease, renal dysfunction(defined as eGFR <30ml/min) or liver dysfunction (AST > 3 times the upper limit of normal) 3.a patient who takes current or past treatment for osteoporosis 4.a patient who takes a drug such as steroid, anticonvulsant, Ca, P, Vitamin D, Vitamin K, multivitamin, or hormone replacement therapy 5.a patient with a malignat tumor 6.a patient who is pregnant, may be pregnant, or breastfeed 7.a patient whose alchohol consumption over 20g/day 8.a smoker 9.a patient who participates another clinical research within 6 months 10.a patient who is determined as inappropriate as a subject for other reasons by investigator

Design outcomes

Primary

Measure	Time frame
We investigate bone microarchitecture assessed by HR-pQCT in adult patients with type 2 diabetes mellitus. And we compare them with healthy subjects.	—

Secondary

Measure	Time frame
We compare the relationship between bone microarchitecture and metabolic markers with healthy subjects.	—

Countries

Japan

Contacts

Public ContactErika Aikawa

Nagasaki University Hospital Department of Endocrinology and Metabolism

erikaaikawa@nagasaki-u.ac.jp095-819-7262

Outcome results