Investigation of the effect of lubrication with KY jelly on the increase in the cuff pressure of endotracheal tube during general anesthesia using nitrous oxide.

Investigation of the effect of lubrication with KY jelly on the increase in the cuff pressure of endotracheal tube during general anesthesia using nitrous oxide. - Investigation of the effect of lubrication with KY jelly on the increase in the cuff pressure of endotracheal tube during general anesthesia using nitrous oxide.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031377

Enrollment

Registered

2018-03-01

Start date

2018-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients (ASA physical status 1 or 2), aged 20 to 80, scheduled for elective surgery under general anaesthesia requiring tracheal intubation.

Interventions

Endotracheal tube with lubrication with 3 g of KY jelly. Endotracheal tube without any lubrication.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients (ASA physical status 1 or 2), aged 20 to 80, scheduled for elective surgery under general anaesthesia requiring tracheal intubation.

Exclusion criteria

Exclusion criteria: ASA physical status more than 3, the history of PONV, laparoscopic surgery, the surgery in the prone position, major cardiovascular surgery, thoracic surgery, morbidly obese subjects (BMI>35), anticipated difficult intubation or the history of difficult intubation and the subjects in whom the use of nitrous oxide is considered inappropriate.

Design outcomes

Primary

Measure	Time frame
The effect of lubrication with KY jelly on the cuff pressure behaviors of the endotracheal tube during nitrous oxide exposure.	—

Secondary

Measure	Time frame
Sore throat and hoarseness after extubation.	—

Countries

Japan

Contacts

Public ContactYukihide Koyama

Mizonokuchi Hospital, Teikyo University School of Medicine Anesthesiology

yukihidekoyama1008@gmail.com044-844-3333

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026