Healthy adults
Conditions
Interventions
Intake of yogurt containing bifidobacterium (concentration of 1 X 10^10 CFU) with inulin (2g) for 2 weeks - Washout 2 weeks, followed by intake of yogurt containing bifidobacterium (concentration of 1
Sponsors
Ezaki Glico Co., Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects whose defecation frequency is more than five times per week.
Exclusion criteria
Exclusion criteria: 1. Subjects regularly use intestinal drugs and laxatives (including strong laxatives). 2. Subjects habitually consume higher amount of alcohol. 3. Subjects who took in food containing and bifidobacteria, and/or enhanced with oligosaccharide, dietary fiber during one week prior to the start of this study and can't stop intake during this study. 4. Subjects who change their life styles during this clinical trial 5. Subjects who have serious diseases requiring an urgent treatment, or who accept severe complication. 6. Subjects who have a medical history of diseases or surgeries affecting digestion, absorption and bowel movement. 7. Subjects who have allergy to test food. 8. Subjects who is pregnant or willing to be pregnant or breast-feeding during this study. 9. Subjects who are participated in other clinical trials that intake/apply any of food, drug, and cosmetics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantification of fecal bifidobacteria using quantitative real-time polymerase chain reaction | — |
Secondary
| Measure | Time frame |
|---|---|
| 16S rRNA gene based metagenome analysis of gut microbiome | — |
Countries
Japan
Contacts
Public ContactTakashi Mawatari
Ezaki Glico Co., Ltd Institute of health science
Outcome results
None listed