Esophageal cancer
Conditions
Interventions
Conventional treatment
In addition to conventional treatment, bukuryoingohangekobokuto is divided into 3 times 7.5 g per day (2.5 g (1 package) once a day), from 2 weeks before operation to 6 weeks af
Sponsors
Department of Education and Support for Regional Medicine. Department of Kampo medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients waiting for chest upper to lower esophageal cancer radical resection 2. Pre treatment cStage:II, III, IVA (except for T4b, N3) TNM classification:T=1-4a, N=0-2, M=0(TNM-UICC 8 th edition) 3. Performance Status:0-2 4. Hospital Anxiety and Depression Scale (HADS): 8 <= 5. 20 years old and over 6. Medical examination classification:outpatient and inpatient 7. Patients who obtain document consent from the principal
Exclusion criteria
Exclusion criteria: 1. Patients who have past history of abdominal surgery 2 Patients who have past history of ileus 3 Patients with concomitant inflammatory bowel disease such as ulcerative colitis and crohn disease 4. Eemergent surgery 5. Patients who took prohibited concomitant drugs 4 weeks before treatment 6. Patients who have past history of radiotherapy and radiation chemotherapy for esophageal cancer 7. Patients who have past history of allergy for other Kampo formulation(s) 8. Patients who have serious concomitant diseases 9. A woman who is pregnant, has a possibility of pregnancy, is within 28 days after birth, is breastfeeding 10. Dementia patients 11. Others, including patients who are unfit for the study as determined by the attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms of feeling, anxiety, water brash | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence frequency of aspiration pneumonia 2. Postoperative hospital stay 3. Abdominal gas volume 4. Inflammatory marker (IL-6,TNFa,G-CSF,WBC) 5. Chest CT 6. Nutritional status (Body weight, BMI, TSF, AMC, Grip strength,In Body Analysis, CONUT, nutrition-related markers) 7. Clinical examination | — |
Countries
Japan
Contacts
Public ContactShin Takayama
Tohoku University Hospital Department of Education and Support for Regional Medicine. Department of Kampo medicine
Outcome results
None listed