Efficacy of macrodissection for detecting EGFR mutation by cobas test

Efficacy of macrodissection for detecting EGFR mutation by cobas test - Macrodissection for detecting EGFR mutation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000031326

Enrollment

200

Registered

2018-02-15

Start date

2017-12-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: EGFR positive lung cancer samples detected by PCR Clump test from January 2007 to January 2017 at the first biopsy by bronchoscopy. Improve version of the PCR Clump test was introduced in October 2013 in our hospital. All the samples before the introduction are retested in the improved version and included when positive.

Exclusion criteria

Exclusion criteria: Patient who reject to be included.

Design outcomes

Primary

Measure	Time frame
The positive rate of EGFR mutation by cobas test before and after macrodissection of bronchoscopic samples with EGFR mutation with PCR Clump.	—

Secondary

Measure	Time frame
Comparing the rate of tumor area to the whole sample on the slide in both EGFR positive samples and negative samples with cobas test.	—

Countries

Japan

Contacts

Public ContactMariko Kogo

Kobe City Medical Center General Hospital Respiratory Medicine

m_k_o_g_o@yahoo.co.jp078-302-4321

Outcome results