Humidification performance of a HME and a heated and humidified high flow (HHHF) for tracheostomized patients with spontaneous breathing

Humidification performance of a HME and a heated and humidified high flow (HHHF) for tracheostomized patients with spontaneous breathing - Humidification performance of a HME and a heated and humidified high flow (HHHF)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031318

Enrollment

Registered

2018-02-15

Start date

2018-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tracheostomized patients with spontaneous breathing

Interventions

HHHF (heated and humidified high flow) was used for 1 hour Optiflow, 40L/min HME (Heat and moisture exchanger) was used for 1 hour Trach vent+ HHHF (heated and humidified high flow) was used for 1 h

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: We included consecutive adult tracheostomized patients with spontaneous breathing who had been weaned from mechanical ventilation in the ICU.

Exclusion criteria

Exclusion criteria: We excluded patients who met the following criteria: 1) aged less than 18 years old, 2) patients who have too much secretions and difficulty in expelling secretions, 3) patients with severe respiratory or hemodynamic instability, 4) who need more than 1L/min of oxygen or fraction of inspired oxygen (FiO2) > 0.25.

Design outcomes

Primary

Measure	Time frame
Absolute humidity	—

Secondary

Measure	Time frame
Tidal volume,end-tidal carbon dioxide (Et CO2), breathing frequency, SpO2, heart rate, and blood pressure.	—

Countries

Japan

Contacts

Public ContactNobuto Nakanishi

Tokushima university hospital Emergency and critical care medicine

nobuto_nakanishi@yahoo.co.jp088-633-9347

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026