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Pre-examination: A confirmatory test for efficacy to skin of the rich nobiletin extract from Shikuwasa.

Pre-examination: A confirmatory test for efficacy to skin of the rich nobiletin extract from Shikuwasa. - Pre-examination: Evaluation of natural beauty ingredient for skin

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000031265
Enrollment
26
Registered
2019-02-15
Start date
2018-01-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Because it is a test for healthy subjects, there is no target disease.

Interventions

Application of lotion containing nobiletin to skin Application of a lotion to the skin

Sponsors

Wellbe Inc.
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Healthy people who do not have severe disease (diabetes, heart disease, liver disease, kidney disease, cancer, etc.) 2. Women who suffer from skin weakness, spots and wrinkles 3. A person who wishes to voluntarily participate in the clinical trial from the age of 40 to 70 and obtain written consent 4. Those who have not changed the basic cosmetics or cosmetics within the first month before the start of the test and those who can not change during the test period 5. The use of basic cosmetics during the examination period can be used only for the test item 6. Persons who do not constantly consume health food or the like considered to have an effect on the skin within one month before commencement of testing 7. Those who have not received any special skin care treatment during the examination from 1 month before the examination 8. Those who can avoid drastic changes in UV exposure such as swimming, mountain climbing, sunbathing, outdoor exercise compared to before the test 9. Persons who can keep constant daily lifestyle during the examination period 10. Study participation of people who are treating mild chronic diseases (hypertension, hyperlipemia, etc.) shall be able to participate at the discretion of the investigator

Exclusion criteria

Exclusion criteria: 1. People with severe diseases (diabetes, heart disease, liver disease, kidney disease, cancer, etc.) and mental disorders 2. One who ingests internal or external medicine for atopic dermatitis, skin diseases such as urticaria, etc, regularly or within 1 month taking 1/3 of the month or more 3. People with skin conditions and skin diseases that may have an impact on the test 4. Cosmetics containing seekers, those who have experienced allergic symptoms in food, people with drug allergy 5. Pregnant women / lactating women and those who wish pregnancy during the examination period 6. Other persons who did not qualify for participation in the exam by the investigator 7. If you are participating in other clinical trials within the past month

Design outcomes

Primary

MeasureTime frame
Skin measurement 1.Stain / wrinkle measurement with Robo SkinAnalyzer 2.Skin viscoelasticity, water content, oil content

Secondary

MeasureTime frame
Result of the questionnaire survey

Countries

Japan

Contacts

Public ContactAbe, Hiroyuki

Wellbe Inc. Clinical Research Division

abe@well-b.jp098-988-9007

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026