The Efficacy and Safety of Cold Snare Endoscopic Mucosal Resection for 10-14mm Flat and Sessile Colorectal Adenomas

The Efficacy and Safety of Cold Snare Endoscopic Mucosal Resection for 10-14mm Flat and Sessile Colorectal Adenomas - ECO trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031248

Enrollment

Registered

2018-02-19

Start date

2018-02-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

10-14mm flat and sessile colorectal adenomas

Interventions

Cold snare endoscopic mucosal resection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Flat and sessile adenomas (10-14 mm in size) 2. 20 years old and more 3. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Synchronous colorectal cancer requiring surgery 2. Inflammatory bowel disease or familial adenomatous polyposis patients 3. Blood coagulation disorder 4. Infectious disease with systemic therapy indicated 5. Hemodialysis 6. Impossible to suspend anticoagulant or antiplatelet medications 7. Others

Design outcomes

Primary

Measure	Time frame
En-bloc complete resection rate by histological examination	—

Secondary

Measure	Time frame
1. Rate of immediate bleeding requiring endoscopic hemostasis 2. Rate of delayed adverse events (perforation, bleeding) 3. Rate of impossible resection 4. En-bloc complete resection rate by endoscopic examination 5. Rate of white protrusions within the cold snare defect 6. Rate of resected specimens containing submucosal layer	—

Countries

Japan

Contacts

Public ContactYohei Yabuuchi

Shizuoka Cancer Center Division of Endoscopy

y.yabuuchi@scchr.jp055-989-5222

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026