Breast Cancer
Conditions
Interventions
IceSense3(IceCureCo.,Israel)
Sponsors
St.Marianna University School of Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1:ECOG Performance Status(PS)0~1 2:Women20to85years old 3:For the first time, it is diagnosed as invasive breast cancer by histologic examination 4:Subtype diagnosis results Hormone receptor positive, HER2 protein expression negative(no DNA amplification), Ki-67<=20% 5:Breast cancer lesions with primary lesions of MMG, US, CT, MRI and lesion spreads of1.5cm or less are the primary lesions. 6:It is diagnosed that there is a high possibility that the sentinel lymph node(SLN)is negative in the preoperative image diagnosis. 7:Sentinel lymph node biopsy and radiation therapy after cryotherapy are possible. 8:There is no systemic infectious disease with poor control9:After sufficient explanation, patient informed consent(IC) was obtained in writing.
Exclusion criteria
Exclusion criteria: 1:If there is an offer to study non-participation from patients, stop this and exclude it from the study. 2:Patient with distant metastasis. 3:Even if we meet the indication criteria 1,2,3 it is diagnosed as invasive lobular carcinoma, invasive micro papillary carcinoma. 4:MMG, US, CT, MRI admitted lymph duct lesions and daughter nodules around. 5:Cases in proximity of frostbite dangerous skin and chest muscle are not indicated. 6:Other things that the doctor in charge considers inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vacuum-assisted biopsy is performed to check whether viable cancer tissue remains 1 month after non-resected ultrasound guided cryotherapy. | — |
Countries
Japan
Contacts
Public ContactHisanori Kawamoto
St.Marianna University School of Medicine Breast Endocrine Surgery
Outcome results
None listed