Comparison of MECHANISM of early and late vascular responses following treatment of ST-elevation Acute Myocardial Infarction with two different everolimus-eluting stents: Randomized controlled trial between biodegradable polymer and durable polymer stent

Comparison of MECHANISM of early and late vascular responses following treatment of ST-elevation Acute Myocardial Infarction with two different everolimus-eluting stents: Randomized controlled trial between biodegradable polymer and durable polymer stent - MECHANISM-AMI-RCT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031186

Enrollment

120

Registered

2018-02-15

Start date

2018-11-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST-elevation acute myocardial infarction (STEMI)

Interventions

durable polymer-based everolimus-etulint stent biodegradable polymer-based everolimus-etulint stent

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with 1)STEMI 2)Confirmation of coronary culprit lesion by angiography which need to be treated with drug-eluting stent 3)required cardiac catheterization after two weeks

Exclusion criteria

Exclusion criteria: Patients with 1)shock 2)left main disease 3)chronic kidney disease (serum Cr 2.0mg/dl) 4)cancer with life expectancy of less than 2 years 5)scheduled surgery within 3 months

Design outcomes

Primary

Measure	Time frame
strut coverage rate at two weeks	—

Secondary

Measure	Time frame
thrombus, dissection, incomplete stent apposition, target lesion revascularization, etc	—

Countries

Japan

Contacts

Public ContactKanako Omiya

Iwate Medical University Division of Cardiology

komoya@iwate-med.ac.jp019-651-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026