Comparison of the effect of desflurane and sevoflurane on postoperative circadian rhthm in patients undergoing total knee arthroplasty

Comparison of the effect of desflurane and sevoflurane on postoperative circadian rhthm in patients undergoing total knee arthroplasty - Effect of anesthetics on postoperative circadian rhythm

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031116

Enrollment

Registered

2018-03-01

Start date

2018-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients undergoing total knee arthroplasty

Interventions

sevoflurane desflurane

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients undergoing total knee arthroplasty

Exclusion criteria

Exclusion criteria: Above ASA PW3, cardiac disease, diabetes mellitus, Sjogren's syndrome, sialolithiasis disease, salivary gland tumor

Design outcomes

Primary

Measure	Time frame
Circadian rhythm of melatonin	—

Secondary

Measure	Time frame
postoperative sleep disturbance	—

Countries

Japan

Contacts

Public ContactToru Komatsu

Aichi Medical University Department of aneshtesia

komatsu-t@umin.ac.jp+81561623311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026