Facial nerve palsy
Conditions
Interventions
Intratympanic dexamethasone application for 10 consecutive days
Sponsors
Nagoya City University, Graduate school of Medical sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients who is diagnosed as Bell's palsy or Ramsay-Hunt syndrome. The patients who can start the protocol within 7 days after onset. 20 years or older
Exclusion criteria
Exclusion criteria: Presence of non-viral inflammation in the idle ear. The presence of the carriage state of viral or bacterial disease. Middle ear or inner ear anomaly which makes it impossible to inject to the middle ear. HbA1C > 6.5% BUN >25 mg/dl or Serum creatinine level>2.0 mg/dl ALT > 100 U/l or AST > 100/l Severe protracted wound healing. Signs of central facial palsy Pregnancy, or possible pregnancy Participate in other clinical traials within 3 months Recurrent facial palsy Treatment other than 60 mg of prednisolone and 1000 mg (Bell's palsy) or 3000 mg (Hunt syndrome)of oral valaciclovir within two days straight History of facial nerve decompression surgery The patients who are considered not to be appropriate for the clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery of the facial nerve grading at 1,3,6,9,12 months after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of complete recovery rate with intervention | — |
Countries
Japan
Contacts
Public ContactAkira Inagaki
Nagoya City University, Graduate school of Medical sciences Department of Otorhinolaryngology, Head and Neck surgery
Outcome results
None listed