Intrapleural fibrinolytic therapy with urokinase.

Intrapleural fibrinolytic therapy with urokinase. - Fibrinolytic therapy with urokinase.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031102

Enrollment

Registered

2018-02-01

Start date

2018-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractory intrathoracic infection

Interventions

Intrapleural injection of 60,000 to 120,000 units of urokinase per day. Injection for 1 to 3 days.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) patient with refractory intrathoracic infection 2) patient with intrathoracic drain 3) hospitalized patient 4) patient with written consent

Exclusion criteria

Exclusion criteria: 1) patient with active intrathoracic bleeding 2) patient that were judged unsuitable by the treating doctor

Design outcomes

Primary

Measure	Time frame
Ratio of patients that were cured without surgical intervention during hospitalization.	—

Countries

Japan

Contacts

Public ContactTakashi Ibe

Gunma University Hospital Division of General Thoracic Surgery

t-ibe@gunma-u.ac.jp027-220-8224

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026