Surgical reconstruction using the human dried amnion of the otolaryngology region

Surgical reconstruction using the human dried amnion of the otolaryngology region - Surgical reconstruction using the human dried amnion of the otolaryngology region

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031097

Enrollment

150

Registered

2018-02-08

Start date

2008-02-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients with the mucosa defect of the otolaryngology region receiving surgical treatment

Interventions

Dried amnion are returned by a saline (or it is the same state) and the affected part are covered by the amnion.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) The patients of (at the agreement acquisition) 20 years old or older age 2) The patients who relatively have good overall status 3) The patients who is judged to be available for observation, the testing that conformed to a study enforcement plan and a survey

Exclusion criteria

Exclusion criteria: 1) The person who judged a doctor to have difficulty in hospital visiting and coming home safely for study period 2) The patients who complicate infection with the activity 3) The patients who plan the enforcement of the operation for the evaluation department effective during study period in (perform a study of the agreement acquisition with starting) 4) For the group medicine of the planned drug (Xylocaine anesthetic agent, Achromycin) to use during study period, is the patients with a history of the drug allergy 5) The patients (saying that, however, the subjects who do not receive the study drug are possible) who participated in other studies or clinical studies within six months 6) Pregnancy or the childbearing patients who may be pregnant or hope for pregnancy during study period or do not use appropriate contraception 7) The patients who judged a doctor to be inadequate as an object of this study in testing at agreement acquisition

Design outcomes

Primary

Measure	Time frame
Day to Epithelization completion after treatment (The epithelization completion defines "the point in time when the summation of each item score became 0" as "epithelization completion" at each evaluation point of "pain, otorrhea, adhesion, color, the neovascularisation".)	—

Secondary

Measure	Time frame
1)Pain 2)otorrhea 3)adhesion 4)color 5)neovascularisation	—

Countries

Japan

Contacts

Public ContactShojyaku Hideo

University of Toyama Dept. of Otolaryngology

hshojaku@med.u-toyama.ac.jp076-434-7367

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026