Randomized controlled trials on the effectiveness of goal directed perfusion

Randomized controlled trials on the effectiveness of goal directed perfusion - Randomized controlled trials on the effectiveness of goal directed perfusion

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031093

Enrollment

300

Registered

2018-02-15

Start date

2018-02-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiovascular disease

Interventions

Maintain oxygen delivery during cardiopulmonary bypass is more than 300 mL/min/m2, through pump flow adjustments. Conventional extracorporeal circulation management (maintain perfusion flow determined

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Subjects aged 20 years or older at the time of consent acquisition 2.Subjects undergoing open heart surgery using a heart-lung machine 3.Subjects who received sufficient explanation before participating in this study and provided written consent with sufficient understanding.

Exclusion criteria

Exclusion criteria: 1.Patients with severe renal impairment (eGFR < 30 mL/min/m2) 2.Patients scheduled to undergo hypothermic extracorporeal circulation (less than 34C) 3.Patients scheduled to undergo circulatory arrest 4.Patients who have been using auxiliary circulation before surgery 5.Other patients who the principal investigator deems inappropriate as subjects

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative acute kidney injury	—

Countries

Japan

Contacts

Public ContactSatoshi Matsushita

Juntendo University Department of Cardiovascular Surgery

saty-m@juntendo.ac.jp03-3813-3111(3335)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026