Comparative evaluation of Laser Bio-Stimulation as an adjunct to Non-Surgical Periodontal Therapy and its effects on Aspartate Aminotransferase levels in the management of Chronic Periodontitis-A Randomized Controlled Trial

Comparative evaluation of Laser Bio-Stimulation as an adjunct to Non-Surgical Periodontal Therapy and its effects on Aspartate Aminotransferase levels in the management of Chronic Periodontitis-A Randomized Controlled Trial - Comparative evaluation of Laser Bio-Stimulation as an adjunct to Non-Surgical Periodontal Therapy and its effects on Aspartate Aminotransferase levels in the management of Chronic Periodontitis-A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031087

Enrollment

Registered

2018-01-31

Start date

2015-11-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Generalized Periodontitis

Interventions

Procedure for laser irradiation The diode laser of 980 nm at a power output of 2.5 W in pulsed mode was used. The tip of the fiber was inserted into the pocket.Each site was radiated for 30 seconds tw

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Case definition as per AAP classification1999. Clinical probing depth 5mm - 7mm Clinical attachment loss atleast 4 mm in at least 2 adjacent sites per tooth Presence of minimum 20 teeth. Radiographic evidence of bone loss.

Exclusion criteria

Exclusion criteria: Patients with systemic conditions like Diabetes, hypertension, atherosclerosis and other systemic diseases known to affect periodontal status. Pregnant LactatingWomen. Use of hormonal contraceptives Pockets of more than 8mm in the studied area Patients with deleterious habits like alcohol consumption , tobacco habits and any other adverse habits. Patients who have received any surgical or non surgical periodontal therapy in past 6 mo nt hs. 7.Patients who have received any antimicrobial therapy in past 6 months.

Design outcomes

Primary

Measure	Time frame
Laser Biostimulation along with Scaling and Root Planing has shown promising results on clinical and biochemical marker evaluation.	—

Secondary

Measure	Time frame
Laser Biostimulation along with Scaling and Root Planing has shown promising results on clinical and biochemical marker evaluation.	—

Countries

Asia(except Japan)

Contacts

Public ContactDr Stuti Gupta

ITS DENTAL COLLEGE,HOSPITAL AND RESEARCH CENTRE Knowledge Park 3

Stutigupta0901@gmail.com9953742797

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026