A study on prediction of myocardial blood flow reserve using cardiac CT in patients with chronic renal failure who are undergoing hemodialysis treatment and suspected exertional angina pectoris

A study on prediction of myocardial blood flow reserve using cardiac CT in patients with chronic renal failure who are undergoing hemodialysis treatment and suspected exertional angina pectoris - Study on myocardial blood flow reserve using cardiac CT in dialysis patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031072

Enrollment

Registered

2018-01-31

Start date

2018-01-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina pectoris

Interventions

Adenosine stress myocardial perfusion scintigraphy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: A. Patients with chronic renal failure who regularly undergo dialysis treatment for more than 1 year B. Patients who are suspected or diagnosed with angina from clinical symptoms. C. Patients who agreed to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Iodine contrast agent Allergic patient 2. History of contrast agent nephropathy 3. History of multiple myeloma or organ transplantation 4. Advanced atrioventricular block 5. Signs of severe symptomatic heart failure. Determination or doubt of moderate or severe aortic valve stenosis 6. History of coronary artery bypass or other cardiac surgery 7. I have undergone coronary intervention within the past 6 months 8. Beta blocker contraindicated patients 9. Patients who are allergic to beta-blockers 10. History of bronchial stroke lung disease 11. Severe chronic obstructive pulmonary disease 12. I think that research researcher may become a problem in other medical conditions or conditions. 13. Patients who have received high dose exposure within 18 months prior to consent: more than one nuclear medicine examination or MDCT or high dose exposure of more than 50 mSv 14. Acute coronary syndrome patients 15. Contraindications to vasodilators: Systolic blood pressure less than 90 mm Hg Dipyridamole and the use of dipyridamole containing drugs Use of methynolexanthin (aminophylline and caffeine) Unstable acute myocardial infarction or acute coronary syndrome Advanced sinus artery (<40 bpm) 16. BMI (bodymass index) 40 or more 17. Severe hepatic disorders that affect drug safety assessment, those suffering from heart disease 18. Patient judged inappropriate at the discretion of the research doctor.

Design outcomes

Primary

Measure	Time frame
Pharmacological stress cardiac CT Pharmacological stress myocardial perfusion scintigraphy CAG	—

Countries

Japan

Contacts

Public ContactHiroki Tanisawa

Showa University Division of Cardiology, Department of Medicine

tanisawa20@med.showa-u.ac.jp+81-3-3784-8000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026