Impacts of pneumatic displacement of submacular hemorrhage secondary to age-related macular degeneration on retinal pigment epithelial detachment

Impacts of pneumatic displacement of submacular hemorrhage secondary to age-related macular degeneration on retinal pigment epithelial detachment - Pneumatic displacement for submacular hemorrhage and retinal pigment epithelial detachment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031065

Enrollment

Registered

2018-01-30

Start date

2009-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exudative age-related macular degeneration

Interventions

Intravitreal injection of SF6 gas and tPA

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Eyes with submacular hemorrhage secondary to exudative age-related macular degeneration

Exclusion criteria

Exclusion criteria: (1) eyes who underwent cataract surgery, (2) intravitreal injection of anti-vascular endothelial growth factor agents, or (3) photodynamic therapy simultaneously with or within a week after pneumatic displacement, (4) who previously underwent vitrectomy, and (5) who required vitrectomy due to vitreous hemorrhage accompanying SRH before or after intravitreal tPA and SF6

Design outcomes

Primary

Measure	Time frame
Prevalence and flattening rate of pigment epithelial detachment	—

Secondary

Measure	Time frame
Postoperative best-corrected visual acuities and the number of additional treatments	—

Countries

Japan

Contacts

Public ContactNagoya City University Graduate School

Medical Sciences Department of Ophthalmology and Visual Science

yasukawa@med.nagoya-cu.ac.jp052-853-8251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026