Impact of varenicline on gastric emptying and effect of domperidone in healthy adults

Impact of varenicline on gastric emptying and effect of domperidone in healthy adults - varenicline and gastric emptying

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031055

Enrollment

Registered

2018-01-30

Start date

2017-12-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

functional gastrointestinal disorder

Interventions

no pretreatment (control) pretreatment of varenicline 0.5mg pretreatment of domperidone 10mg pretreatment of varenicline 0.5mg with domperidone 10mg

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Adults not having gastrointestinal symptoms, and not taking prescription of gastrointestinal drugs or anti-psychological drugs.

Exclusion criteria

Exclusion criteria: Adults with current gastrointestinal disorders or past history of upper gastrointestinal operation.

Design outcomes

Primary

Measure	Time frame
Comparison of gastric parameters (gastric emptying parameter, t-half) among different pretreatments (control, varenicline, domperidone, varenicline with domperidone)	—

Countries

Japan

Contacts

Public ContactTakatsugu Yamamoto

Teikyo University School of Medicine Department of Internal Medicine

ymmt@med.teikyo-u.ac.jp03-3964-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026