The efficacy and safety of trans-catheter embolization for inferior mesenteric artery and lumbar artery to prevent persistent type 2 endoleak prior to endovascular abdominal aortic aneurysm repair (EVAR) with Endurant2 stent-graft:multicenter prospective study

The efficacy and safety of trans-catheter embolization for inferior mesenteric artery and lumbar artery to prevent persistent type 2 endoleak prior to endovascular abdominal aortic aneurysm repair (EVAR) with Endurant2 stent-graft:multicenter prospective study - TAE for IMA and LA prior to EVAR(Endurant)study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000031042

Enrollment

100

Registered

2018-03-01

Start date

2018-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal aortic aneurysm

Interventions

Trans-catheter embolization for inferior mesenteric artery and lumbar artery with metalic coil prior to EVAR with Endurant2 stent-graft

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The formation of abdominal aortic aneurysm is within the instruction for use (IFU) of Endurant2 stent-graft system. The patients who is out of indication for open surgical repair, or refuse open surgical repair. The patients who have sufficient renal function (eGFR above 30) The patent branch vessels originated from aneurysm is at least above one confirmed with preoperative CT image. ECOG performance status is 0 or 1.

Exclusion criteria

Exclusion criteria: Rupture case The severe stenosis or occlusion of superior mesenteric artery The bilateral occlusion of internal iliac artery Uncontrollable of heart failure, angina pectoris, and arrhythmia despite of treatment Concomitant with active cancer Sever drug allergy

Design outcomes

Primary

Measure	Time frame
The incidence of EL2 after EVAR in 6 months	—

Secondary

Measure	Time frame
The incidence of EL2 after EVAR in 1 year Technical success rate of IMA/LA embolization Safety of IMA/LA embolization Aneurysm diameter after EVAR within 30days, 6 month and 1 year Aneurysm related death after EVAR within 30days, 6 month and 1 year Re-intervention rate for EL2 after EVAR within 30days, 6 month and 1 year	—

Countries

Japan

Contacts

Public ContactYamaguchi Masato

Kobe University Hospital Department of Radiology

masato03310402@yahoo.co.jp078-382-6104

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026