Healthy postmenopausal women
Conditions
Interventions
30 women taking 3 capsules of equol(total dose of 10 mg) and lactobionic acid daily for 12 weeks
30 women not taking the above supplementation
Sponsors
Supplement department, Advanced Medical Care Inc.
Hamamatsucho Hamasite Clinic, Midtown Clinic Medical Corporation
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: -Healthy postmenopausal (primary) women aged 50 years and above -Those undergoing medical checkup at Sendai medical Center -Those who can come to the clinic every month since the beginning of the study to have interview or investigations -Those who can take the supplementation daily and take daily notes throughout the study period (12 weeks)
Exclusion criteria
Exclusion criteria: -Those with history of allergy to soy foods, dairy products or Brewer's yeast -Those who start taking medications or functional food that could affect the result of the study -Those under hormone replacement therapy or medications that could affect the blood hormone level -Others identified inappropriate by the investigator physicians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparisons from baseline in the results of blood lipids (TG, HDL-C, LDL-C, T-CL), uric acid, hemoglobin A1c, arterial stiffness (baPWV), visceral fat area, and markers related to bone metabolism (vitamin D, PTH) after supplementation with equol and lactobionic acid for 12 weeks as well as comparisons based on background characteristics | — |
Secondary
| Measure | Time frame |
|---|---|
| Cor-relations between advanced glycation end products, dietary factors and equol producer status as well as types of microflora Comparison from baseline in the results of menopausal rating scale after supplementation with equol and lactobionic acid every four weeks Monitoring of adverse effects of supplementation every four weeks | — |
Countries
Japan
Contacts
Public ContactMegumi Kato
Shinkokai Medical Corporation Sendai General Health Screening Clinic
Outcome results
None listed