Measurement serum concentration of ropivacaine during awake craniotomy to investigate appropriate amount of ropivacaine

Measurement serum concentration of ropivacaine during awake craniotomy to investigate appropriate amount of ropivacaine - Measurement serum concentration of ropivacaine during awake craniotomy to investigate appropriate amount of ropivacaine

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030896

Enrollment

Registered

2018-01-22

Start date

2018-04-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain tumor which should be resected under awake craniotomy

Interventions

We are going to use ropivacaine for local anesthesia upper 3.6mg/kg at awake craniotomy,and measure of serum concentration of ropivacaine(arterial blood) 15minites after injection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are going to have the awake craniotomy at Nagoya university hospital. 1)Age 18yo to 70yo 2)ASA PS 1,2,3 3)Patient who agreed this research by informed consent and the document

Exclusion criteria

Exclusion criteria: 1)Patients who don't agreed. 2)have a liver disfunction. 3)have a allergy for the ropivacaine and other local anesthetics. 4)have a disfunction of anticoagulants 5)have a severe respiratory disorder. 6)have a heart failure. 7)Other factor which patients can't be in candidate at this study decided by the doctor

Design outcomes

Primary

Measure	Time frame
Measurement of serum concentration of ropivacaine(at arterial blood),	—

Countries

Japan

Contacts

Public ContactSato Takehito

Nagoya university graduate school of medicine Department of anesthesiology

takesato@med.nagoya-u.ac.jp052-744-2341

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026