A non-randomized confirmatory trial of Cold Snare Polypectomy for Superficial Non-Ampullary Duodenal Epithelial Tumor (D-COP trial)

A non-randomized confirmatory trial of Cold Snare Polypectomy for Superficial Non-Ampullary Duodenal Epithelial Tumor (D-COP trial) - A non-randomized confirmatory trial of Cold Snare Polypectomy for Superficial Non-Ampullary Duodenal Epithelial Tumor (D-COP trial)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030876

Enrollment

330

Registered

2018-01-18

Start date

2018-01-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Superficial non-ampullary deuodenal epithelial tumor (SNADET)

Interventions

DCSP

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) superficial non-ampullary duodenal epithelial tumor <= 10mm 2) bulbs ~ 3rd part of deudenum 3) 3 lesions or less 4) lesion expected to remove en-block using snare 5) 20 years old and more 6) can be followed for 12 months 7) Written informed consent

Exclusion criteria

Exclusion criteria: 1) FAP patients 2) Impossible to suspend anticoagulant or antiplatelet medications (except low-dose aspirin) 3) Infectious disease with systemic therapy indicated 4) Psychosis 5) Systemic steroids medication 6) History of myocardial infarction within 6 months or unstable angina pectoris within 3 weeks 7) Severe respiratory disease requiring continuous oxygen therapy 8) Uncontrollable hypertension 9) others

Design outcomes

Primary

Measure	Time frame
the rate of local recurrence in 12 months	—

Secondary

Measure	Time frame
Delayed perforation and bleeding	—

Countries

Japan

Contacts

Public ContactKOHEI TAKIZAWA

Shizuoka Cancer Center Division of Endoscopy

k.takizawa@scchr.jp055-989-5222(ext.2270)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026