Amide proton transfer imaging for malignant brain tumor and spinal tumor

Amide proton transfer imaging for malignant brain tumor and spinal tumor - Amide proton transfer imaging for malignant brain tumor and spinal tumor

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000030794

Enrollment

Registered

2018-01-15

Start date

2017-11-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignant brain tumor, spinal tumor

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who will undergo surgical resection, or chemotherapy or radiotherapy for malignant brain tumor or spinal tumor 2. Patients with written informed consent

Exclusion criteria

Exclusion criteria: 1. Patients with heart pacemaker 2. Patients with metallic foreign body, such as cochlea implant, etc. 3. Patients with severe claustrophobia 4. Patients who may not keep rest on the bed

Design outcomes

Primary

Measure	Time frame
Correlation between APT image and cellularity and mitotic activity	—

Secondary

Measure	Time frame
1. Comparison between APT image and diffusion weighted image and Positron emission tomography (PET) image 2. Correlation between early change of APT image after chemoradiotherapy and progression free survival time and overall survival time	—

Countries

Japan

Contacts

Public ContactMakoto Ohno

National Cancer Center Hospital Department of Neurosurgery and Neuro-Oncology

mohno@ncc.go.jp03-3542-2511

Outcome results