Assessment of individualized positive end-expiratory pressure on respiratory mechanics and ventilation distribution in morbidly obese patients during laparoscopic surgery

Assessment of individualized positive end-expiratory pressure on respiratory mechanics and ventilation distribution in morbidly obese patients during laparoscopic surgery - Effect of PEEP during laparoscopic surgery in obese patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030787

Enrollment

Registered

2018-01-12

Start date

2018-01-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obese

Interventions

Measure each parameter during spontaneous breathing in Spine position.(T1) Measure each parameter after intubation under PEEP10 cmH2O during general anesthesia.(T2) First RM followed by a decrementa

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Morbidly obese patients with a BMI > 35 kg / m2 undergoing laparoscopic surgery Informed consent ASA-PS:1-2

Exclusion criteria

Exclusion criteria: Pulmonary comorbidities COPD grade < 3, or FEV1s < 1000 ml Heart failure cardiac index < 1.8 L/m2, NYHA >2 Poorly controlled hypertension

Design outcomes

Primary

Measure	Time frame
Assess change of ventilation distribution in dorsal part of lung during individualized PEEP	—

Secondary

Measure	Time frame
Select individualized PEEP and assess change of trans pulmonary pressure during head down and pneumoperitonium.	—

Countries

Japan

Contacts

Public ContactNozomi Katayama

Shimane University Faculty of medicine Department of Anesthesiology

nk600113@med.shimane-u.ac.jp0853-20-2295

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026