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Effects of narrow-band ultraviolet-B irradiation on gene expression of histamine H1 receptor and allergy-related cytokines induced by artificial exposure of Japanese cedar pollen in nasal mucosa in of patients with pollinosis in the off-season.

Effects of narrow-band ultraviolet-B irradiation on gene expression of histamine H1 receptor and allergy-related cytokines induced by artificial exposure of Japanese cedar pollen in nasal mucosa in of patients with pollinosis in the off-season. - Effects of narrow-band ultraviolet-B irradiation on gene expression of histamine H1 receptor and allergy-related cytokines induced by artificial exposure of Japanese cedar pollen in nasal mucosa in of patients with pollinosis in the off-season.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000030765
Enrollment
20
Registered
2018-02-19
Start date
2018-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis (pollinosis)

Interventions

Intranasal irradiation of narrow-band ultraviolet-B at a dose of 150mJ/cm2 once a day for 3 days

Sponsors

University of Tokushima
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients with pollinosis.

Exclusion criteria

Exclusion criteria: Patients who was excluded by investigators

Design outcomes

Primary

MeasureTime frame
Gene expression of histamine H1 receptor and allergy-related cytokines (IL-4, 5 and 9) of the nasal mucosa

Secondary

MeasureTime frame
The allergic rhinitis symptoms including sneezing, nasal discharge and nasal obstruction

Countries

Japan

Contacts

Public ContactNoriaki Takeda

University of Tokushima School of Medicine Department of Otolaryngology

takeda@tokushima-u.ac.jp088-633-7169

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026