Exploratory study of onset predictor and drug resistor factors of central nerve system metastasis by omics methods, using cerebrospinal fluid.

Exploratory study of onset predictor and drug resistor factors of central nerve system metastasis by omics methods, using cerebrospinal fluid. - Exploratory study of onset predictor and drug resistor factors of central nerve system metastasis.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000030756

Enrollment

Registered

2018-01-20

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with primary lung cancer as pathological (cytology or / and histology) examination. 2) Cases suspected of meningeal carcinomatosis as an image or symptom, requiring cerebrospinal fluid examination. 3) Adult cases of ages 20 and older sufficient to be able to confirm that agreement was made based on own judgment which has cognitive ability which can fully understand the contents and properties of this research

Exclusion criteria

Exclusion criteria: 1) Case in which lumbar puncture and cerebrospinal fluid sampling can not be performed due to some reason (insufficient examination position, danger of cerebral hernia due to puncture, etc.)). 2) Cases judged by the attending doctor that there is a problem with the ability to consent or to understand the study plan. 3) Cases with unstable mental disorders. 4) Other cases that the attending doctor judged inappropriate, in this study

Design outcomes

Primary

Measure	Time frame
Detection of biomarkers involved in affinity of tumor cells to the central nervous system.	—

Secondary

Measure	Time frame
Detection of factors involved in resistant to the anti-cancer agents of central nervous system metastasis.	—

Countries

Japan

Contacts

Public ContactYusuke Tsukagoshi

Gunma University Hospital Division of Allergy and Respiratory Medicine, Integrative Center Of Internal Medicine

y.tsukagoshi@gunma-u.ac.jp027-220-8123

Outcome results