Tissue distribution after intravenous dosing of liposomal amphotericin B in deep-seated mycoses

Tissue distribution after intravenous dosing of liposomal amphotericin B in deep-seated mycoses - Dstribution of liposomal amphotericin B

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000030745

Enrollment

Registered

2019-04-01

Start date

2024-03-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

deep-seated mycoses

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Cases of deep-seated mycoses or fungal endophthalmitis which were resistant to systemic L-AMB administration and required surgical treatment such as vitrectomy, or enucleation.

Exclusion criteria

Exclusion criteria: Cases in which patient consent was not obtained or the attending physician deemed invalid due to various reasons.

Design outcomes

Primary

Measure	Time frame
the concentartion of L-AMB in tha plasma and tissues after the last intravenous injection	—

Secondary

Measure	Time frame
beta-D-glucan isolated organism drug susceptibility visual acuity	—

Countries

Japan

Contacts

Public ContactKiyofumi Mochizuki

Gifu University Graduate School of Medicine Department of Ophthalmology

mochi-gif@umin.ac.jp058-230-6288

Outcome results