Relationship between ALDH2 and ADH1B phenotypes and circadian variation of endogenous ethanol and acetaldehyde

Relationship between ALDH2 and ADH1B phenotypes and circadian variation of endogenous ethanol and acetaldehyde - Relationship between ALDH2 and ADH1B phenotypes and circadian variation of endogenous ethanol and acetaldehyde

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030687

Enrollment

Registered

2018-01-05

Start date

2018-01-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A healthy adult

Interventions

Intervention is straight for 2 days. A subject is sampled his/her breath 4 times for the 2 days

on rising (5:00~7:00), before lunch (11:00~13:00), before dinner (17:00~19:00) and before retiring (23:00~25:00). Sampling is taken after at least 3 h of fasting and 1 h of washing mouth. A subject ab

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ?20<= years-old ?Male and Female ?A person who is provided sufficient explanations about this study and consented to it in writing by his/her own free will

Exclusion criteria

Exclusion criteria: ?an inappropriate person for this study ?a person who has any airway diseases or liver diseases

Design outcomes

Primary

Measure	Time frame
Breath endogenous alcohol and acetaldehyde concentrations	—

Secondary

Measure	Time frame
ADH1B and ALDH2 genotypes	—

Countries

Japan

Contacts

Public ContactAyako Himemiya-Hakucho

Graduate School of Medicine, Yamaguchi University Department of Legal Medicine

haku.a@yamaguchi-u.ac.jp0836-22-2234

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026