healthy subjects
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients who are over 20 years of age at the time of consent acquisition 2) Gender: No prejudice 3) Patients who got document consent by their own voluntary intention
Exclusion criteria
Exclusion criteria: 1) Patients with drug hypersensitivity such as allergies 2) Peripheral arterial disease, those with ischemia (Fontaine 3-4) 3) Persons with heart failure (NYHA 4) 4) Persons who are pregnant or may be 5) Persons who have severe respiratory illness 6) Patients who are difficult to apply paste such as large skin ulcers or marked skin diseases 7) Patients who are deemed inappropriate by researchers or doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of blood flow by carbon dioxide paste application in healthy subjects Safety by carbon dioxide paste application in healthy subjects | — |
Countries
Japan
Contacts
Kobe University Graduate School of Medicine Department of Oral and Maxillofacial Surgery