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Exploratory clinical trials evaluating the effectiveness and safety of carbon dioxide paste for healthy subjects

Exploratory clinical trials evaluating the effectiveness and safety of carbon dioxide paste for healthy subjects - Exploratory clinical trials evaluating the effectiveness and safety of carbon dioxide paste

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000030662
Enrollment
10
Registered
2019-01-01
Start date
2018-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy subjects

Interventions

Application of carbon dioxide paste Apply carbon dioxide paste once on the skin of the lower leg or cervix for 20 minutes. Apply evenly using the fingers as the application method.

Sponsors

Kobe University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients who are over 20 years of age at the time of consent acquisition 2) Gender: No prejudice 3) Patients who got document consent by their own voluntary intention

Exclusion criteria

Exclusion criteria: 1) Patients with drug hypersensitivity such as allergies 2) Peripheral arterial disease, those with ischemia (Fontaine 3-4) 3) Persons with heart failure (NYHA 4) 4) Persons who are pregnant or may be 5) Persons who have severe respiratory illness 6) Patients who are difficult to apply paste such as large skin ulcers or marked skin diseases 7) Patients who are deemed inappropriate by researchers or doctors

Design outcomes

Primary

MeasureTime frame
Improvement of blood flow by carbon dioxide paste application in healthy subjects Safety by carbon dioxide paste application in healthy subjects

Countries

Japan

Contacts

Public ContactTakumi Hasegawa

Kobe University Graduate School of Medicine Department of Oral and Maxillofacial Surgery

hasetaku@med.kobe-u.ac.jp078-382-6213

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026