Effect of resistance training and essential amino acids intake in elderly diabetes patients with sarcopenia

Effect of resistance training and essential amino acids intake in elderly diabetes patients with sarcopenia - Effect of resistance training and amino acids intake in elderly diabetes patients with sarcopenia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000030639

Enrollment

Registered

2019-01-01

Start date

2018-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Control Conventional method Intervention 1 Resistance exercise using rubber tube for 20 to 30 minutes a day. Intervention 2 Resistance exercise using rubber tube for 20 to 30 minutes a day and take

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Outpatients with type 2 diabetes 2) over 70 and under 80 years old 3) Patient suspected of Sarcopenia 4) Patients without cognitive dysfunction (MMSE score of 24 or more) 5) Patients who are capable of making a decision by themselves, and provide written cosent.

Exclusion criteria

Exclusion criteria: 1) Patients with type 2 diabetes 2) Patients without cognitive dysfunction (MMSE 23 points or less) 3) Patients who should ban or limit exercise therapy.Severe ketosis and fasting blood glucose 250 mg or more.Fresh ocular bleeding due to proliferative retinopathy.Severe renal dysfunction.Ischemic heart disease and disorder of cardiopulmonary.Bone and joint disease.Severe infection.Diabetic gangrene.Advanced diabetes autonomic disorder. 4)Patients who are receiving the following diabetes drugs. SGLT2 inhibitor, Pioglitazone, GLP-1 receptor agonist.

Design outcomes

Primary

Measure	Time frame
Changes of the changes in quadriceps muscle strength before and after 1-year intervention	—

Secondary

Measure	Time frame
1)The change of HbA1c by the 1-year intervention. 2)The change in total body muscle mass evaluated by dual-energy x-ray absorptiometry(DEXA) by the 1-year intervention. 3)Physical activity amount evaluated by physical activity meter 4)The change in total body muscle mass evaluated by Bioelectrical Impedance Analysis (BIA) 5)The changes in bone density evaluated by DEXA and in bone metabolism markers 6)Evaluation of mood change using GDS, SF36v2 7)Comparison of differences in quadriceps muscle strength between the elastics training groups and control groups	—

Measure

Time frame

1)The change of HbA1c by the 1-year intervention. 2)The change in total body muscle mass evaluated by dual-energy x-ray absorptiometry(DEXA) by the 1-year intervention. 3)Physical activity amount evaluated by physical activity meter 4)The change in total body muscle mass evaluated by Bioelectrical Impedance Analysis (BIA) 5)The changes in bone density evaluated by DEXA and in bone metabolism markers 6)Evaluation of mood change using GDS, SF36v2 7)Comparison of differences in quadriceps muscle strength between the elastics training groups and control groups

—

Countries

Japan

Contacts

Public ContactShin Kawanabe

St.Marianna University School of Medicine Division of Metabolism and Endocrinology, Department of Internal Medicine

s2kawanabe@marianna-u.ac.jp044-977-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026