Biomarker testing for Personalized Therapy in real world setting; First line treatment decision in the advanced non-squamous NSCLC

Biomarker testing for Personalized Therapy in real world setting; First line treatment decision in the advanced non-squamous NSCLC - BRAVE-Study Biomarker testing for Personalized Therapy in real world setting; First line treatment decision in the advanced non-squamous NSCLC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000030618

Enrollment

200

Registered

2017-12-28

Start date

2018-01-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-squamous Non-small-cell lung carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients with histologically confirmed non-squamous NSCLC who initiated first-line therapy between August 1, 2017 and December 31, 2017 2.Participants with locally advanced or metastatic non-squamous NSCLC at the diagnosis who were not indicated for radical surgery or radiotherapy 3.Patients with ECOG PS of 0-1 at the time of diagnosis 4.Patients who provided consent to participate in this study (However, in case of death or lost to follow-up, instructions from the Institutional Review Board at each site should be followed)

Exclusion criteria

Exclusion criteria: 1.Patients with postoperative recurrence 2.Patients enrolled in clinical trials of an unapproved drug as first-line therapy for advanced NSCLC 3.Patients otherwise considered unsuitable to participate in this study by investigators at study sites

Design outcomes

Primary

Measure	Time frame
Proportion of patients who could select first-line treatment based on the results of biomarker testing	—

Countries

Japan

Contacts

Public ContactNobuyoshi Hatanaka

Linical Co.,Ltd. Contract Medical Affairs Clinical Trial Division

hatanaka-nobuyoshi@linical.co.jp+81-6-6150-2210

Outcome results